Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes
Authors: Alcantara LC, de Oliveira T, Gordon M, Pybus O, Mascarenhas RE, Seixas MO, Goncalves M, Hlela C, Cassol S, Galvao-Castro B.
Journal: AIDS, 20(5):780-2 (2006)
DOI: https://doi.org/10.1097/01.aids.0000216383.14808.13
Abstract
We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu-Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup.
The presence of South African sequences in two different clusters from Brazil, and the finding of the beta-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil
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Citation: Alcantara LC, de Oliveira T, Gordon M, Pybus O, Mascarenhas RE, Seixas MO, Goncalves M, Hlela C, Cassol S, Galvao-Castro B. Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes AIDS, 20(5):780-2 (2006).